Look to the main chance.

Understand the thought

Meaning in plain English

Pay attention to the opportunity or interest that matters most to your purpose. The advice favors practical focus, while leaving open whether pursuing that advantage is fair or worth its costs.

What the words are saying

The main chance is read as the central opportunity for advancing one’s situation. The instruction asks someone not to become distracted by smaller details while a consequential choice is available. It can support sensible planning, such as protecting the essential aim of a project. It can also sound narrowly self-interested when gain becomes the only standard. The useful question is what truly matters and what a person would sacrifice to obtain it. Focusing on an advantage need not mean disregarding promises, relationships or the people affected by a decision.

Everyday example

An organiser protects the event’s accessibility budget instead of spending it on an impressive decoration.

When to use it

Use it to refocus attention on a central practical aim.

Agent-assisted editorial interpretation. This explains the words; it does not by itself verify their author or earliest origin.